Important copyright and AI information

Please be reminded that unauthorised reproduction of the Manual in any form, including creation of summaries, audio or animation, is not permitted,
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Dedication
This manual is dedicated to the memory of Dr Edward William Brentnall FACEM, MBE, OAM, KStJ 05/08/1929-01/10/2024. Ed was a guiding light for generations of emergency physicians who sheltered, mentored and inspired many of us. See the full dedication here.

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Latest updates

General anaesthesia for clot retrieval in stroke

The Stroke management page has been updated with additional information about the beneficial effects of general anaesthesia in clot retrieval for stroke.

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Thrombectomy in basilar artery occlusion

The Management of stroke page has been updated with additional information about the benefits of thrombectomy in basilar artery occlusion.

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PPIs and gastric cancer risk

The Peptic ulcer disease page has been updated with a revised section on the risk (or now thought not) of gastric cancer following prolonged PPI use.

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Benefits of regional anaesthesia for fractured neck of femur

The Femoral fractures page has been updated with additional information about the benefits of regional anaesthesia for fractured neck of femur.

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Reverse total shoulder replacement dislocation

The Glenohumeral joint dislocations page has been updated with information about reverse total shoulder replacement dislocation.

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Surgical management of humeral head fractures

The Shoulder and arm injuries page has been updated with additional information about surgical management of humeral head fractures.

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Evidence for thrombolysis in stroke page removed

The Evidence for thrombolysis in stroke page has been removed as contemporary management of stroke involving perfusion scanning means earlier research is now of limited applicability. However if you want a quick summary – the early research of tPA in stroke was drug company funded, heavily biased, and had highly deceptive reporting of results in … Read more

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ACEM Nov 2025 statement on thrombolysis in stroke

A segment on the ACEM 2025 statement on thrombolysis in stroke has been added to the Thrombolysis in stroke page.

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