24/5/26 Diphtheria alert 

There is currently an outbreak of Diphtheria in parts of the Northern Territory, Western Australia and South Australia. Please be alert for cases of oropharyngeal and cutaneous Diphtheria in patients who have been to these regions, particularly Indigenous patients.

Important copyright and AI information

Please be reminded that unauthorised reproduction of the Manual in any form, including creation of summaries, audio or animation, or copying content into any machine learning tool is not permitted. Breaches of this agreement will result in immediate, and permanent, termination of access and legal action for breach of copyright.

Dedication
This manual is dedicated to the memory of Dr Edward William Brentnall FACEM, MBE, OAM, KStJ 05/08/1929-01/10/2024. Ed was a guiding light for generations of emergency physicians who sheltered, mentored and inspired many of us. See the full dedication here.

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Latest updates

Paediatric sepsis management

The Management of sepsis page has been updated with additional paediatric recommendations, based on the 2026 Paediatric surviving sepsis guidelines.

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Old definitions of sepsis removed

The Assessment of sepsis page has been updated with the removal of the old definitions of sepsis.

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Definitions of sepsis

The Assessment of sepsis page has been updated with some refinement of the definitions of sepsis.

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History in assessment of volume status

The Assessment of intravascular volume page has been updated with a new short segment on history.

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NEWS 2 sepsis scoring system

The Physiological disturbance scores page has been updated with information about the NEWS2 scoring system for sepsis.

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Sepsis scoring systems

The Assessment of sepsis page has been updated with additional information about sepsis scoring systems.

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Unproven therapies in sepsis

The Management of sepsis page has been updated with additional information about unproven therapies in sepsis, and information about some of these therapies has been removed.

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IV fluids in sepsis

The Management of sepsis page has been updated with additional information about IV fluids in sepsis.

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