Angioedema

The Angioedema page has been updated, with particular reference to the role of icatibant in the treatment of life threatening angioedema.

Litigation

Just to start the year off on a cheery note, some additional information about litigation for negligence has been added to the Medicolegal issues page.

The real incidence of multi-phasic anaphylaxis

Despite being widely quoted as having an incidence of 2-30%, multi-phasic anaphylaxis that is clinically significant now appears to have an incidence of about 0.4% for cases of anaphylaxis and 0.1% for cases of allergy in ED patients. Hopefully this will reverse the trend of prolonged observation of patients with non life-threating allergic reactions. This information … Read more