DVT

An anatomical classification of lower limb DVT has been added.

Biliary disease

Updated info regarding formation of gallstones and diagnostic accuracy of US following recently published review.

p wave dispersion in AFib

New section outlining the association between p wave dispersion and the progression to chronic Afib in the Atrial fibrillation section.

Delta gap

A new section and table relating to the use of the Delta gap in metabolic acidosis has been added to the Metabolic acidosis section.

Developmental milestones

A more detailed table of developmental milestones for children has been added as a new page link from “Developmental milestones” in the Assessment of Children section.

True vs false labour

A table outlining the difference in the nature of contractions between true and false labour has been added to the Labour section.

Immature platelet fraction

Information about the immature platelet fraction and how it can help differentiate causes of thrombocytopenia has been added to the Thrombocytopenia section.

Codeine metabolism

Updated information regarding variations in metabolism of codeine in the Opioid Toxicity section of the Toxicology chapter.

IABP in cardiogenic shock

Updated sections with new evidence from an RCT of IABP published recently in Journal of Intensive Care Medicine that did not show any overall mortality benefit from IABP. Patients < 50 years of age did have better outcomes however the power of the study was inadequate to indicate if this is a real difference.