hsTnI 1 hour rule out strategy

The Risk stratification in suspected ACS page has been updated, including information about the use of a hsTnI 1 hour rapid ACS diagnostic pathway. The proposed pathway appears to be not as useful as similar hsTnT pathways. Neumann, JT, Sörensen, NA, Schwemer, T, et al. Diagnosis of Myocardial Infarction Using a High-Sensitivity Troponin I 1-Hour … Read more

Pre PCI beta blockers

The Management of acute coronary syndromes page has been updated with additional information about the role of pre-PCI beta blockers. Roolvink, V, Ibanez, B, Ottervanger, JP, et al. Early Administration of intravenous Beta blockers in patients with ST-elevation myocardial infarction before primary PCI. Journal of the American College of Cardiology 2016.

Myoglobin in ACS

The Other cardiac biomarkers page has been updated with additional information about the role of myoglobin in excluding ACS in low risk patients. Meek, R, Braitberg, G, Cullen, L, et al. Outcome at 30 days for low-risk chest pain patients assessed using an accelerated diagnostic pathway in the emergency department. Emerg Med Australas 2016.

Subsegmental PE

Additional information about the management of isolated subsegmental PE has been added to the Management of PE page. Kearon, C, Akl, EA, Ornelas, J, et al. Antithrombotic therapy for vte disease: Chest guideline. Chest 2016 .

Clinical assessment of suspected ACS

The Clinical assessment of ACS page has been updated with revised information regarding LRs for ACS from the following article. Fanaroff, AC, Rymer, JA, Goldstein, SA, et al. Does This Patient With Chest Pain Have Acute Coronary Syndrome?: The Rational Clinical Examination Systematic Review. JAMA 2015;314(18):1955-65. http://www.ncbi.nlm.nih.gov/pubmed/26547467.