Immune checkpoint therapy complications
A new segment on Immune checkpoint therapy complications has been added to the Other oncologic emergencies page.
Haematology
Sinusoidal obstruction syndrome
The Bone marrow transplantation page has been updated with additional information about sinusoidal obstruction syndrome.
D dimer cut off values in PE
The Pulmonary embolism and Deep venous thrombosis pages have been updated with additional information about the various d dimer cut off levels that can be used to determine the need for further imaging.
Iron deficiency anaemia
The Microcytic anaemia page has been updated with a number of small pieces of additional information.
Duration of neutropenia following chemotherapy
The Febrile neutropenia page has been updated with information about the duration of neutropenia following chemotherapy.
Essential thrombocythaemia
The Thrombocytosis page has been updated with additional information about incidence and classification.
Platelet count and bleeding risk
The Thrombocyopenia page has been updated with some additional information about bleeding risk and platelet count.
Haemolytic anaemia
The Haemolytic anaemia page has had a minor update.
ITP
The ITP page has been revised and updated. Of particular note is the increased risk of VTE in patients with chronic ITP.
Antiphospholipid syndrome
The Thrombophilia page has been updated with some additional information about antiphospholipid syndrome
Clinical probability adjusted D dimer levels
The Deep venous thrombosis page has been updated with a short segment on clinical probability adjusted D dimer levels to trigger further imaging in suspected VTE.
Thrombocytosis
The Thrombocytosis page has had some minor updates.
ESR
The Other investigations page has been updated with more factors that affect the ESR.
B12 deficiency
The Macrocytic anaemia page has been updated with additional information about Vitamin B12 deficiency.
DOACs in pregnancy
The Other anticoagulants and Drugs in pregnancy and lactation pages have been updated with information about the use of DOACs in pregnancy.
Andexanate
The Reversal of anticoagulation page has been updated with additional information about the effect of andexanate in patients with DOAC associated bleeding.
Aplastic anaemia
The Normochromic anaemia page has been updated with some minor changes to the segment on Aplastic anaemia.
Clotting factor replacement
The Clotting factor replacement page has had a number of small changes to improve clarity.
Reversal of anticoagulation
The Reversal of anti-coagulation page has been revised, updated and made more concise.
Rivaroxaban blood levels
The Other anticoagulants page has been updated with information about expected therapeutic rivaroxaban levels.