Diffuse cutaneous mastocytosis
The Mastocytosis page has been updated with some additional information about diffuse cutaneous mastocytosis.
Immunology
Cephalosporin cross reactivity
The Specific allergens page has been updated with additional information about allergic cross reactivity between penicillins and cephalosporins.
Delayed phase anaphylaxis
The Anaphylaxis page has been updated to better emphasise the rarity of delayed phase anaphylaxis in ED patients and to avoid routine long periods of observation for patients with anaphylaxis otherwise improved with therapy.van der Zwet, K. V. M., van Vossen-Treur, D., Venema, E., Guillen, S., & Moore-van Leest, E. J. (2022). Biphasic Allergic Reactions … Read more
Anaphylaxis epidemiology
The Anaphlyaxis page has been updated with some additional information about epidemiology,
Histiocytosis
The Other autoimmune inflammatory diseases page has been updated with a short segment on histiocytosis.
SLE testing
The SLE page has had a number of updates regarding testing.
Features of Giant cell arteritis
The Giant cell arteritis page has been updated with some additional information about diagnostic features.
Anaphylaxis
The Anaphylaxis page has been revised, wording improved and key points added.
Features of anaphylaxis
The Anaphylaxis page has been updated with additional information about the features of anaphylaxis and their frequency.
SLE
The SLE page has had a few minor updates.
Ocular granulomatosis with polyangiitis
The Wegner’s granulomatosis (aka Granulomatosis with polyangiitis) page has been updated with additional information about orbital involvement.
Complement and angioedema
A table describing the changes in complement components in the different types of angioedema has been added to the Angioedema page.
Giant cell arteritis
Some minor updates and reorganisation of the Giant cell arteritis page have been made.
Anxiety instead of anaphylaxis or angioedema
The Anaphylaxis page has been updated with additional information about how to differentiate anxiety from anaphylaxis or angioedema. This is particularly important as a significant proportion of younger patients who present with ‘impending allergic airway obstruction’ are actually suffering from anxiety. The use of adrenaline (and icatabant) does not help anxiety.
Corticosteriods
A specific segment on corticosteriods has been added to the Immunosuppressants page.
Corticosteroid psychosis
A short segment on corticosteriod psychosis has been added to the Immunosuppressants page
Cephalosporin allergy
The Specific allergens page has been updated with information about cephalosporin allergy.
Ig4 related disease
The Other autoimmune inflammatory diseases page has been updated with a segment on Ig4 related disease.
Sarcoid lung disease
The Sarcoidosis page has been updated with some additional information about sarcoid lung disease
Antihistamines in anaphylaxis
The Anaphylaxis page has been updated with information about the limited role of antihistamines in the treatment of anaphylaxis.