Angioedema
The Angioedema page has been updated, including more information about the treatment of idiopathic angioedema.
Immunology
Mast cell tryptase
The Immunological investigations page has been updated with some new information about mast cell tryptase.
Tocilizumab for giant cell arteritis
The Giant cell arteritis page has been updated, including the addition of tocilizumab therapy to management.
Eosinophillic granulomatosis with angiitis
The Other autoimmune inflammatory diseases page has been updated with additional information about eosinophillic granulomatosis with angiitis (also known as Churg Strauss syndrome).
Wegener’s granulomatosis images
A CXR and CT demonstrating pulmonary granulomas have been added to the Wegener’s granulomatosis page.
EMG in polymyositis – correction
The Polymyalgia rheumatica page has been updated and the statement that EMG is usually normal in polymyalgia rheumatica has been corrected. EMG is usually abnormal in up to 10% of patients with the disease.
Prevalence of immunosuppression
The Immunodeficiency page has been updated with information about the prevalence of immunosuppression.
Polymyalgia rheumatica
The Polymyalgia rheumatica page has been revised and updated.
Mixed systemic sclerosis
The Scleroderma page has been updated with some additional information about diagnostic testing for the condition.
ESR and CRP in SLE – correction
A correction has been made to the Systemic lupus erythematosus page. CRP does not correlate with disease activity, but ESR does (not the other way round as stated previously).
Polymyalgia rheumatica
The Polymyalgia rheumatica page has been updated after the publication of the review: Owen, CE, Buchanan, RR, Hoi, A. Recent advances in polymyalgia rheumatica. Intern Med J 2015;45(11):1102-8.
Steroids don’t reduce ED representations following allergy
The role of steroids in not preventing ED re-attendances following allergy has been added to the Anaphylaxis page. Grunau, BE, Wiens, MO, Rowe, BH, et al. Emergency Department Corticosteroid Use for Allergy or Anaphylaxis Is Not Associated With Decreased Relapses. Annals of Emergency Medicine;66(4):381-89. http://dx.doi.org/10.1016/j.annemergmed.2015.03.003.
Penicillin vs cephalosporin hypersensitivity
The Specific allergens page has been updated with information about how penicillin and cephalosporin hypersensitivity differ.
Icatibant in ACE induced angioedema
Some additional information about the efficacy of icatibant in patients with ACE induced angioedema has been added to the Angioedema page. Bas, M, Greve, J, Stelter, K, et al. A randomized trial of icatibant in ACE-inhibitor-induced angioedema. N Engl J Med 2015;372(5):418-25. http://www.ncbi.nlm.nih.gov/pubmed/25629740.
Tryptase for the diagnosis of anaphylaxis
The Immunological investigations page has been revised, including additional information about the use of serum tryptase for the diagnosis of anaphylaxis.
sIgE
The Immunological investigations page has been revised, including the addition of a segment on sIgE testing.
Kawasaki disease
The Other inflammatory conditions page has been updated with additional information about Kawasaki disease.
Henoch Schönlein purpura
The Other inflammatory conditions page has been updated with additional information about HSP.
Mastocytosis
The Mastocytosis page has been updated with some information about Cutaneous mastocytosis and other rarer types of mastocytosis