CT in CAP

Some additional information about the test characteristics of CT chest for the diagnosis of CAP has been added to the Community acquired pneumonia page. Claessens, Y-E, Debray, M-P, Tubach, F, et al. Early Chest Computed Tomography Scan to Assist Diagnosis and Guide Treatment Decision for Suspected Community-acquired Pneumonia. American Journal of Respiratory and Critical Care … Read more

ECG findings in PE

The section on the ECG findings in PE on the Investigations in PE – non imaging page has been revised considering the information from the following article: Shopp, JD, Stewart, LK, Emmett, TW, et al. Findings From 12-lead Electrocardiography That Predict Circulatory Shock From Pulmonary Embolism: Systematic Review and Meta-analysis. Acad Emerg Med 2015;22(10):1127-37. http://www.ncbi.nlm.nih.gov/pubmed/26394330.

Steroids for severe CAP

The Management of CAP page has been updated with information about the beneficial role of steroids in hospitalised patients with severe CAP. Siemieniuk, RAC, Meade, MO, Alonso-Coello, P, et al. Corticosteroid Therapy for Patients Hospitalized With Community-Acquired Pneumonia. A Systematic Review and Meta-analysis. Annals of Internal Medicine 2015.

D dimer in pregnancy

The PE in special populations page has been updated with particular reference to d dimer levels during pregnancy. Some relevant references are: Greer, IA. Pregnancy Complicated by Venous Thrombosis. New England Journal of Medicine 2015;373(6):540-47. http://www.nejm.org/doi/full/10.1056/NEJMcp1407434. Kline, JA, Williams, GW, Hernandez-Nino, J. D-dimer concentrations in normal pregnancy: new diagnostic thresholds are needed. Clin Chem 2005;51(5):825-9. … Read more

IV steroids in severe CAP

The Management of CAP page has been updated with some information about the use of IV steroids in a selected population of patients with severe CAP. Bottom line is – sounds interesting, but not enough evidence currently to change practice.