Nitrofurantoin
A new segment on Nitrofurantoin has been added to the Other antimicrobials page
Bob Dunn
Asymptomatic gallstones
The Biliary disease page has been updated with some information about the natural history of asymptomatic gallstones.
Subsegmental PE
Additional information about the management of isolated subsegmental PE has been added to the Management of PE page. Kearon, C, Akl, EA, Ornelas, J, et al. Antithrombotic therapy for vte disease: Chest guideline. Chest 2016 .
Isolated below knee DVT
Additional information about the risk factors for propagation, and treatment of, isolated below knee DVT has been added to the Management of DVT page.
Anti-coagulant choices in DVT
A new section better outlining the choice of anti-coagulants in DVT has been added to the Management of DVT page.
Management of DVT
A new page called Management of DVT has been created with the content being moved from the Deep venous thrombosis page.
More NOACs
More changes have been made to the Other anticoagulants page, including an upgrading of rivaroxaban or apixaban to the preferred anti-coagulants for non valvular AF and VTE treatment.
Splenic embolisation
The Splenic trauma page has been updated with some additional information about the role of embolisation.
Takostubo cardiomyopathy
Some additions have been made to the segment on Takotsubo cardiomyopathy in the MINOCA page.
Hypertonic saline in bronchiolitis
A slight change indicating the possible utility of neubulised hypertonic saline in bronchiolitis has been added to the Bronchiolitis page.
Intra-articular steroids for OA
The Osteoarthritis page has been updated with information about the utility of intra-articular steroids for symptom control.
NOAC drug interactions
More detail regarding potential drug interaction with NOACs has been added to the Other anticoagulants page.
CT in SAH – clarification
A statement on the Investigation of suspected subarachnoid haemorrhage page has been clarified. The statement ‘aneurysm may infrequently be seen if > 5 mm diameter’, in relation to CT head has been corrected to ‘aneurysm may occasionally seen if > 5 mm diameter’. Thanks to Raymund for picking this up.
Central cord syndrome – correction
The segment on central cord syndrome on the Spinal cord injury page has been corrected to reflect that weakness from central cord syndrome is greater distally than proximally in the limbs. Previously this was indicated to be the other way around due to the mistaken use of a ‘>’ sign instead of a ‘<‘ sign. … Read more
Chikungunya disease
A new topic on Chikungunya disease has been added to the Infectious diseases section
Zika virus
A new topic on Zika virus has been added to the Infectious diseases section.
New content quiz February 2016
The February 2016 update quiz can be found here
Rifampicin and NOACs – correction
A mistake in the Other anticoagulants page has been identified and corrected. Rifampicin is an inducer of NOAC metabolism, not an inhibitor of it.
NOAC pharmacology
A table outlining the different pharmacology of the most common NOACs has been added to the Other anticoagulants page.
NOAC monitoring table
A table outlining the different methods of monitoring NOAC therapy has been added to the Other anticoagulants page.