Anticoagulation in AF and ESRF

The Cerebrovascular disease page has been updated with revised information about anticoagulation for patients with AF and end stage renal failure. Dahal, K, Kunwar, S, Rijal, J, et al. Stroke, Major Bleeding, and Mortality Outcomes in Warfarin Users With Atrial Fibrillation and Chronic Kidney Disease: A Meta-Analysis of Observational Studies. Chest 2016;149(4):951-59. 

MRI for appendicitis

The Appendicitis page has been updated with new test characteristics of MRI. Petkovska, I, Martin, DR, Covington, MF, et al. Accuracy of Unenhanced MR Imaging in the Detection of Acute Appendicitis: Single-Institution Clinical Performance Review. Radiology 2016;279(2):451-60.  

New journal scans pages

Two new journal scan pages have been created that contain the latest abstracts from all the journals most relevant to Emergency Medicine. One is called Emergency Medicine Journals and the other General Journals. Each has a series of tabs across the top of the page – click on the relevant tab to see the latest … Read more

Improved menu structure

The Menu displayed on the header bar on each page of the front part of the website has been improved to enable better navigation of the web features. Because of the improved menu system we have removed the links to the different web features from the text on the top of the front page.

Half strength apple juice for ORT

The Paediatric gastroenteritis page has been updated with information about the efficacy of half strength apple juice for ORT in children with only mild dehydration. Freedman, SB, Willan, AR, Boutis, K, et al. Effect of dilute apple juice and preferred fluids vs electrolyte maintenance solution on treatment failure among children with mild gastroenteritis: A randomized … Read more

Low dose tPA for stroke

Some information about low dose (0.6mg/kg) IV tPA for the treatment of stroke has been added to the Thrombolytic therapy in stroke page. Anderson, CS, Robinson, T, Lindley, RI, et al. Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke. N Engl J Med 2016.

Below knee DVT complication rates

The Management of DVT page has been updated with the rates of complications revised downwards from those previously quoted. Horner, D, Hogg, K, Body, R. Should we be looking for and treating isolated calf vein thrombosis? Emergency Medicine Journal 2016;33(6):431-37.

Don’t transfuse platelets to patients with ICH on antiplatelet agents

The Platelet transfusion and Stroke management pages have been updated with information from the PATCH RCT published in Lancet that demonstrated an increase in disability and mortality from platelet transfusion in patients with supratentorial ICH on mostly aspirin, clopidogrel and/or dipyridamole. The exact mechanism for this is unclear. Baharoglu, MI, Cordonnier, C, Salman, RA-S, et al. … Read more

Single value hsTnI rule out strategy

The Troponins in ACS page has been updated with some additional information about single value hsTnI to rule out ACS. The bottom line is that hsTnT is probably more sensitive than hsTnI for clinically significantly outcomes, so is currently preferred. Carlton, E, Greenslade, J, Cullen, L, et al. Evaluation of High-Sensitivity Cardiac Troponin I Levels … Read more

hsTnI 1 hour rule out strategy

The Risk stratification in suspected ACS page has been updated, including information about the use of a hsTnI 1 hour rapid ACS diagnostic pathway. The proposed pathway appears to be not as useful as similar hsTnT pathways. Neumann, JT, Sörensen, NA, Schwemer, T, et al. Diagnosis of Myocardial Infarction Using a High-Sensitivity Troponin I 1-Hour … Read more