tPA for stroke between 3-4.5 hours

Some additional information about the role of tPA in patients selected without advanced imaging (e.g. CT perfusion, DWI MRI) between 3-4.5 hours has been added to the Thrombolytic therapy in stroke page following the BMJ article published today that does not support the evidence for the use of tPA for this time window.

VRE

A new page called Drug resistant organisms has been created from the old Drug resistant Staph Aureus page and a short section on VRE has been added to it.

MINOCA

The section on Myocardial ischaemia and non-obstructive coronary arteries on the Coronary artery disease page has been updated with additional information regarding prognosis and causes.

Anthrax

Some minor additions have been made to the Anthrax and other pages relating to potential biological warfare agents following a review on the matter recently published in the NEJM.