Na valproate toxicity
The Anticonvulsant toxicity page has been updated with some additional information about the potential toxic dose of Na valproate.
Updates
micro RNA mir 122 in paracetamol poisoning
The Paracetamol page has been updated with some additional information about micro RNA mir 122.
Antihistamines in anaphylaxis
The Anaphylaxis page has been updated with information about the limited role of antihistamines in the treatment of anaphylaxis.
Constipation
The Causes of abdominal pain page has been updated with some additional information about the treatment of constipation.
Disposition in pericarditis
The Pericarditis page has been updated, including with a segment on disposition. Thanks to Farzad for the suggestion.
IV catheter failure and amount in vein
The Difficult IV access page has been updated with information about the amount of catheter in the vein and failure rate, following US guided access.
HOCM
The Cardiomyopathy page has been updated with a few additions to the segment on HOCM.
Differential BP in aortic dissection
The Thoracic aortic dissection page has been modified, including some additional information about differential BP and pulse deficits.
Encephalitis
The Encephalitis page has been updated, including some minor changes to its epidemiology.
Appendicitis
A number of improvements in wording and formatting on the Appendicitis page have been made.
More about MAC values
The Inhalational anaesthetic agents page has been updated with some additional information about MAC values.
Erythema multiforme, SJS/TEN
The Blistering skin rashes page has had a major overhaul in the areas of EM, SJS/TEN.
Bristol stool chart
The Assessment of abdominal pain page has been updated with the addition of the Bristol stool chart used to describe stool type.
Serum lactate and Hartmann’s administration
The Metabolic acidosis page has been updated with some additional information about how large volumes of Hartmann’s solution may contribute to lactic acidosis. Zitek, T, Skaggs, ZD, Rahbar, A, et al. Does Intravenous Lactated Ringer’s Solution Raise Serum Lactate? J Emerg Med 2018
Lactic acidosis
The Metabolic acidosis page has been updated with some additional causes of lactic acidosis.
Enhanced peritoneal stripe sign
The US of the bowel page has been updated with additional information about the enhanced peritoneal stripe sign of pneumoperitoneum.
ECG changes of RV infarction
The ECG in ACS page has been updated with some additional information about ECG changes in RV infarction, as well as some improved formatting.
Patterns of LFT abnormality table
The table of patterns of LFT abnormality on the Liver function tests page has been extensively revised and updated.
AST/ALT ratio and LDH
The Liver function tests page has been updated with some additional information about the AST/ALT ratio and causes of LDH elevation.
SAAG and protein content
The Ascites page has had a few minor updates, including making it clearer that high SAAG means low ascitic fluid protein content and vice versa.