Updates

The Thrombolytic Therapy for Stroke page has been updated with recommendations for the administration of tPA in patients taking antiplatelet and anti-coagulant agents. (Link)

The page Thrombolytic Therapy in Stroke has been substantially revised and incorporates the results from the 18 month follow up of patients in the IST3 trial published recently in Lancet Neurology. As is common with tPA stroke trials, much of the relevant data is not easily found (in the study appendix in this case). The results suggest … Read more

The journal watch pages have been updated with the following improvements: The Journal of Trauma and Resucitation have been added to the Emergency Medicine Journal page. (Link) JAMA has been added to the International Journal page (Link) The Australasian Journal of Radiology and the Australian Journal of Rural Health have been added to the Australasian … Read more

The role of clopidogrel and aspirin in stroke prevention has been udated in light of the CHANCE trial published in the NEJM yesterday.(Link)

Following an inquiry from one of our subscribers, a short segment has been added to the section on setting up a ventilator in the Ventilation page in the Resuscitation section. (Link).

A short section about high sensitivity troponin has been added to the Cardiac Biomarkers page. Link

A small section on traumatic SAH has been added to the Complications of Head Trauma page. Link

Salt ingestion is an uncommon cause of hypernatraemia, but 0.75 – 3g/kg can be potentially fatal. One tablespoon of salt weighs about 15 g. Link

How the LP RBC counts may influence the diagnosis of SAH has been added following a recent study in Academic Emergency Medicine. Link

Despite diltiazem having a theorretical advantage of causing less hypotension, a retrospective study in Academic Emergency Medicine did not show any signfiicant differences in outcomes in patients with AFib treated with dilatiazem, verpapamil or metoprolol. Link 

The upgrade to the new website is now (almost) complete. All areas appear to be functioning well, however there still are a few formatting issues that should be resolved over the next few days. In particular, the bullets on some lists seem to want to have different sizes, and some hyperlinks want to underline themselves – but … Read more

The Extracorporeal methods of drug elimination page in the Toxicology section has had a major update following the recent symposium on the subject in Copenhagen.

The Salicylates page in the Toxicology section has been updated.

The Oral hypoglycaemic Agents page in the Endocrinology section has been updated with particular reference to the metformin toxicity.

A short segment on the thenar eminence technique of bag mask ventilation has been added to the Bag Mask Ventilation page in the Resuscitation section.

A short segment on the effects of non O blood group on risk of VTE has been added to the Thrombophilia page in the Haematological Disorders section.