Hyperosmolar therapy of raised ICP

Updated sections on ‘Prevention of secondary brain injury’ and Resusciation fluids’ following the latest review of hyper osmolar therapy published recently in the NEJM.

tPA in stroke

The section on Thrombolysis in stroke has been updated following release of the IST3 trial and accompanying meta-analysis of tPA for the treatment of stroke that casts doubts over the efficacy of tPA after 3 hours.