Neurology

A small segment on drug induced amnesia has been added to the Cerebral lobe function page. 

The Myasthenia gravis page has been extensively revised and updated.

The Lumbar puncture page has been updated with some additional information about the role of US in performing LP in infants.

The Stroke management page has been updated to indicate that the association between GA and poorer outcome for interventional stroke treatment is no longer thought to exist. Schonenberger, S, Uhlmann, L, Hacke, W, et al. Effect of Conscious Sedation vs General Anesthesia on Early Neurological Improvement Among Patients With Ischemic Stroke Undergoing Endovascular Thrombectomy: A … Read more

The Stroke page has been updated with a revision of the segment on stroke mimics.

The Spontaneous intracerebral haemorrhage page has been updated with a segment on seizures following ICH. The page name has also been changed to Spontaneous intracerebral haemorrhage from its previous title of Intracerebral haemorrhage to differentiate it from traumatic ICH. Please be aware that links to this page from our quizzes may be broken as a … Read more

The Stroke management page has been updated following the new evidence suggesting that clot retrieval (in appropriately selected cases) may improve outcome if it can be commenced within 7 hours 18 minutes. Saver, JL, Goyal, M, van der Lugt, A, et al. Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis. JAMA … Read more

The Polio page has been updated with current information about the 3 countries that still have wild type Polio.

Details about direction fixed and direction changing nystagmus have been included on the Cerebellar function page.

The Vertigo page has been updated following the recent publication of the following article. Edlow, JA, Newman-Toker, D. Using the Physical Examination to Diagnose Patients with Acute Dizziness and Vertigo. Journal of Emergency Medicine. 2016;50(4):617-28.

The Cerebrovascular disease page has been updated with additional information about the primary prevention of stroke. Steiger, N, Cifu, AS. Primary prevention of stroke. JAMA 2016;316(6):658-59.

The Stroke management page has been revised to indicate that the target sBP value for the management of primary ICH is < 180mmHg and that reductions to 110-140mmHg appear to confer no additional benefit. Qureshi, AI, Palesch, YY, Barsan, WG, et al. Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage. N Engl J Med 2016.

The Cerebrovascular disease page has been updated with information about the equivalence of ticagrelor and aspirin for the prevention of stroke. Johnston, SC, Amarenco, P, Albers, GW, et al. Ticagrelor versus Aspirin in Acute Stroke or Transient Ischemic Attack. New England Journal of Medicine;2016.

The Seizures page has been updated with a segment on seizures in pregnancy. Kinney, MO, Morrow, J. Epilepsy in pregnancy. BMJ 2016:i2880

A segment on Stiff person syndrome has been added to the Other movement disorders page.

The Cerebrovascular disease page has been updated with revised information about anticoagulation for patients with AF and end stage renal failure. Dahal, K, Kunwar, S, Rijal, J, et al. Stroke, Major Bleeding, and Mortality Outcomes in Warfarin Users With Atrial Fibrillation and Chronic Kidney Disease: A Meta-Analysis of Observational Studies. Chest 2016;149(4):951-59. 

The Cerebrovascular disease page has been updated with revised information about the effectiveness of aspirin for stroke prevention in patients with TIA.