Seizures and driving
The segment on seizures and driving restrictions on the Management of isolated seizures page has been updated with reference to the Austroads: Assessing fitness to drive publication.
Neurology
Low dose tPA for stroke
Some information about low dose (0.6mg/kg) IV tPA for the treatment of stroke has been added to the Thrombolytic therapy in stroke page. Anderson, CS, Robinson, T, Lindley, RI, et al. Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke. N Engl J Med 2016.
ACEM position on thrombolysis in stroke
Information regarding the position on ACEM on tPA for the treatment of stroke has been updated on the Thrombolytic therapy in stroke page.
Don’t transfuse platelets to patients with ICH on antiplatelet agents
The Platelet transfusion and Stroke management pages have been updated with information from the PATCH RCT published in Lancet that demonstrated an increase in disability and mortality from platelet transfusion in patients with supratentorial ICH on mostly aspirin, clopidogrel and/or dipyridamole. The exact mechanism for this is unclear. Baharoglu, MI, Cordonnier, C, Salman, RA-S, et al. … Read more
Status epilepticus
The Status epilepticus page has been updated including new information about the relative efficacy of different anti-convulsant agents.
Deficit resolution in ICH
A statement about how approximately 0.5% of patients with ICH may have transient neurological deficits has been added to the Intracerebral haemorrhage page.
Hypomelanosis of Ito
The Phakomatoses page has been updated with a segment on Hypomelanosis of Ito.
Statin myopathy
A small segment on statin induced autoimmune myopathy has been added to the Neuropathies and myopathies page.
Deep brain stimulation
A short segment about deep brain stimulation and it’s potential adverse effects has been added to the Parkinson’s disease page.
CT in SAH – clarification
A statement on the Investigation of suspected subarachnoid haemorrhage page has been clarified. The statement ‘aneurysm may infrequently be seen if > 5 mm diameter’, in relation to CT head has been corrected to ‘aneurysm may occasionally seen if > 5 mm diameter’. Thanks to Raymund for picking this up.
Peripheral neuropathy
The Peripheral neuropathy page has been revised and updated following the recent JAMA article: Callaghan, BC, Price, RS, Feldman, EL. Distal Symmetric Polyneuropathy: A Review. JAMA 2015;314(20):2172-81.
Charcot-Marie-Tooth disease
A short segment on Charcot-Marie-Tooth disease has been added to the Peripheral neuropathy page.
CT image of slit ventricles
A CT image of slit ventricles has been added to the Cerebral ventricular shunts page.
Arachnoid cyst images
2 CT images of an arachnoid cyst have been added to the Cerebral tumours page.
Bell’s palsy
The Assessment of facial weakness page has been updated with additional information about Bell’s palsy.
Dextromethorphan/quinidine for agitated dementia
The Altered mental state page has been updated with information about the use of dextromethorphan/quinidine for behavioural control. Cummings, JL, Lyketsos, CG, Peskind, ER, et al. Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial. JAMA 2015;314(12):1242-54. http://www.ncbi.nlm.nih.gov/pubmed/26393847.
Neuroimaging of children with a first non-provoked seizure
The Assessment of isolated seizures page has been updated with additional information about the role of neuroimaging in children following a first non-provoked seizure.
MRI of cerebellar infarction
An MRI demonstrating a cerebellar infarct has been added to the Stroke syndromes page.
Dense basilar artery sign
A plain CT image demonstrating a dense basilar artery sign has been added to the Stroke syndromes page.
Assessment of vision in young children
The Assessment of vision page has been updated with some additional information about the assessment of vision in young children following a recent BMJ article on the subject. Blaikie, AJ, Dutton, GN. How to assess eyes and vision in infants and preschool children. BMJ 2015;350:h1716.