Neurology

The Stroke management page has been updated with a new summary of the results and implications of the many endovascular clot retrieval trials recently published.

The Stroke management page has been updated to reflect the new sBP target of <140mmHg in patients with primary ICH.

The Subarachnoid haemorrhage page has been updated with some additional details about the epidemiology and natural history of intracerebral aneurysms following a recent guideline published on the topic. Thompson BG, Brown RD, Jr., Amin-Hanjani S, et al. Guidelines for the Management of Patients With Unruptured Intracranial Aneurysms: A Guideline for Healthcare Professionals From the American … Read more

The Encephalitis page has been extensively revised and added to following the recent publication of Australasian guidelines on the subject in the MJA.

The Stroke management page has just been updated to reflect the recent recommendation to lower sBP to < 140mmHg in patients with ICH and no contra-indications.

Some additional information about the investigation of intracerebral haemorrhage has been added to the Intracerebral haemorrhage page.

A focused list of the differential diagnoses of a thunderclap headache has been added to the Subarachnoid haemorrhage page.

A short segment on Reversible cerebral vasoconstriction syndrome has been added to the Subarachnoid haemorrhage page.

A segment on Inclusion body myositis has been added to the new Inflammatory myopathies page page.

The Management of isolated seizures page has been updated with additional information regarding prognosis.

The Secondary headaches page has been updated with additional information about the treatment of trigeminal neuralgia, especially neurosurgical techniques of treatment.

The Thrombolytic therapy in stroke page has been updated with the removal of lacunar stroke from the list of stroke types unlikely to benefit from tPA following the publication of an IST-3 subgroup analysis.

Some additional information about the role of tPA in patients selected without advanced imaging (e.g. CT perfusion, DWI MRI) between 3-4.5 hours has been added to the Thrombolytic therapy in stroke page following the BMJ article published today that does not support the evidence for the use of tPA for this time window.

The Stroke Management, Thrombolytic therapy in stroke and Investigation of stroke pages have been updated following publication of the EXTEND 1A trial in the NEJM today showing substantial benefit for endovascular intervention following tPA in patients selected by CT perfusion to be likely to have benefit.

The Investigation of stroke page has been updated with additional information about the sensitivity of CT in acute ischaemic stroke.

The Cerebrovascular disease page has been updated with details of the common normal aortic arch variants.

Details on the role of intra-arterial therapy for stroke has been added to the Stroke management page.