ECG findings in PE

The section on the ECG findings in PE on the Investigations in PE – non imaging page has been revised considering the information from the following article: Shopp, JD, Stewart, LK, Emmett, TW, et al. Findings From 12-lead Electrocardiography That Predict Circulatory Shock From Pulmonary Embolism: Systematic Review and Meta-analysis. Acad Emerg Med 2015;22(10):1127-37. http://www.ncbi.nlm.nih.gov/pubmed/26394330.

Dextromethorphan/quinidine for agitated dementia

The Altered mental state page has been updated with information about the use of dextromethorphan/quinidine for behavioural control. Cummings, JL, Lyketsos, CG, Peskind, ER, et al. Effect of Dextromethorphan-Quinidine on Agitation in Patients With Alzheimer Disease Dementia: A Randomized Clinical Trial. JAMA 2015;314(12):1242-54. http://www.ncbi.nlm.nih.gov/pubmed/26393847.

2015 ILCOR guidelines

The Basic life support and Advanced cardiac life support pages have been updated to incorporate the 2015 ILCOR guidelines. Neumar, RW, Shuster, M, Callaway, CW, et al. Part 1: Executive Summary: 2015 American Heart Association Guidelines Update for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation 2015;132(18 suppl 2):S315-S67. http://circ.ahajournals.org/content/132/18_suppl_2/S315.short.

D dimer in aortic dissection

The Thoracic aortic dissection page has been updated with revised information about the utility of D dimer in the diagnosis. Asha, SE, Miers, JW. A Systematic Review and Meta-analysis of D-dimer as a Rule-out Test for Suspected Acute Aortic Dissection. Annals of Emergency Medicine;66(4):368-78. http://dx.doi.org/10.1016/j.annemergmed.2015.02.013.

PCR/ESI-MS

The Nucleic acid amplification techniques page has been updated with additional information about the utility of polymerase chain reaction followed by electrospray ionization- mass spectrometry (PCR/ESI-MS) in the diagnosis of infection. Vincent, JL, Brealey, D, Libert, N, et al. Rapid Diagnosis of Infection in the Critically Ill, a Multicenter Study of Molecular Detection in Bloodstream … Read more