Hydroxycobalamin adverse effects
Some additional details about the (mostly red discolouration) adverse effects of hydroxycobalamin has been added to the Cyanide page.
Bob Dunn
Cost effectiveness analysis
The Financial issues page has been updated with additional information about different forms of cost effectiveness analysis.
Supracondylar fractures
The segment on Supracondylar fractures on the Elbow injuries page has been updated including more specific information about reduction of these injuries in the ED
Molluscum contagiousum
A segment on Molluscum contagiosum has been added to the General Dermatology page.
Candidiasis
A short new topic on Candidiasis has been added to the Infectious diseases section.
Peri-prosthetic joint infections
A short segment on periprosthetic joint infections has been added to the Septic arthritis page.
Assessment of sepsis
The Assessment of sepsis page has been updated with some additional information about the diagnostic accuracy of CRP and PCT. Enguix-Armada, A, Escobar-Conesa, R, La Torre, AG, et al. Usefulness of several biomarkers in the management of septic patients: C-reactive protein, procalcitonin, presepsin and mid-regional pro-adrenomedullin. Clin Chem Lab Med 2016;54(1):163-8.
Polycystic kidney disease
The Polycystic kidney disease page has been revised and updated following the recent review article: Simms, RJ. Autosomal dominant polycystic kidney disease. BMJ 2016;352:i679. .
Legionnaires disease
The Infectious agents causing CAP page has been updated with additional information about Legionnaires disease.
PCT in febrile infants
The Febrile child page has been updated with additional information about the diagnostic accuracy of PCT in the diagnosis of serious bacterial infection.
Salter Harris Type 1 management
Some additional information about the management of suspected Salter Harris Type 1 injuries has been added to the Assessment of fractures and dislocations page.
Risks for upper GI rebleeding
The Upper GI haemorrhage page has been updated with additional information about the risk of rebleeding.
Risk factors for negligence in doctors
The Negligence segment in the Medicolegal issues page has been revised and some additional information about the risk factors for negligence claims in doctors added.
Night shift effects
The Rosters page has been revised and information about the effects of night shift on driving performance added. Lee, ML, Howard, ME, Horrey, WJ, et al. High risk of near-crash driving events following night-shift work. Proceedings of the National Academy of Sciences 2016;113(1):176-81.
Compassion fatigue
A small segment on Compassion fatigue has been added to the Work stress page.
Cyanide – anion gap acidosis – correction
The Cyanide page has been updated to correct the statement that cyanide causes a non-anion gap acidosis -it causes an anion gap acidosis as stated elsewhere on the page.
Apixaban/Rivaroxaban overdose
A small segment on the usually benign course of rivaroxaban or apixaban overdose as a single ingestion in otherwise healthy people has been added to the Reversal of anti-coagulation page.
Procedural sedation
The Procedural sedation page has been revised and estimated complication rates from ED sedation in adults have been added. Bellolio, MF, Gilani, WI, Barrionuevo, P, et al. Incidence of Adverse Events in Adults Undergoing Procedural Sedation in the Emergency Department: A Systematic Review and Meta-analysis. Academic Emergency Medicine 2016
Diagonal branch of LAD occlusion
A short segment outlining the ECG features of a first diagonal branch LAD occlusion has been added to the ECG in acute coronary syndromes page.
Spinal canal stenosis
A short segment on spinal canal stenosis has been added to the Lower back pain page.