Possible interruption to subscriptions to the Manual

Work is currently being done on the payment system for the Emergency Medicine manual, and this may interrupt your ability to subscribe to the manual.  It is also possible that subscriptions will not be able to be processed between 2nd – 4th October. If you are planning to subscribe or renew your subscription, we suggest you … Read more

Correction – adrenaline/noradrenaline dose in bradycardia

There is an error on the Bradycardias page for the adrenaline/noradrenaline dose.The incorrect adult dose of ‘5-10 microg/kg/min. and increasing by 2.5-5migrog/kg/min. every 5 min.‘ should be replaced to the correct dose of ‘5-10 microg/min. and increasing by 2.5-5migrog/min. every 5 min‘.The text will be corrected with the next file upload.Many thanks to Desmond for … Read more

Andexanet for ICH in patients on DOACs

The Management of stroke page has been updated with some information about andexanet for the treatment of ICH in patients taking DOACs – there is insufficient evidence of benefit to recommend it at present. Future trials will need to be better designed than this one. Connolly, S. J., Sharma, M., Cohen, A. T. et al., … Read more

Metformin

The Other hypoglycaemic agents page has been updated with additional information about metformin, particularly regarding its relative lack of benefits compared to newer agents.