Warfarin

The Warfarin page has been updated with some additional information about target ranges for mechanical valves and reduction of restriction of DOAC therapy on valvular AF.

Risk of asymptomatic cerebral artery aneurysm rupture

The rates of rupture of asymptomatic cerebral artery aneurysm rupture in asymptomatic patients has been revised on the Subarachnoid haemorrhage page, following the publication of a meta analysis on the subject. Malhotra, A, Wu, X, Forman, HP, et al. Growth and rupture risk of small unruptured intracranial aneurysms: A systematic review. Annals of Internal Medicine … Read more

Broken links fixed

We have just noticed that a number of links from various pages on the site were broken. We think we have either fixed all of these or removed any links no longer active. Please let us know if you spot any broken links we might have missed.

Effects of moderate drinking on cognition

The Ethanol page has been updated with additional information about the effects of chronic moderate ethanol ingestion on cognition. Topiwala, A, Allan, CL, Valkanova, V, et al. Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study. BMJ 2017;357:j2353

Adenosine following cardiac transplantation

Adenosine has long been considered contraindicated in transplanted hearts, but this is now being questioned in young patients. The Cardiac transplantation page has been updated to reflect this. Flyer, JN, Zuckerman, WA, Richmond, ME, et al. Prospective Study of Adenosine on Atrioventricular Nodal Conduction in Pediatric and Young Adult Patients After Heart Transplant. Circulation 2017 … Read more